Poor Survival Associated with the <i>BRAF</i> V600E Mutation in Microsatellite-Stable Colon Cancers

S. Samowitz, Wade; Sweeney, Carol; S. Herrick, Jennifer; Albertsen, Hans; R. Levin, Theodore; A. Murtaugh, Maureen; K. Wolff, Roger; L. Slattery, Martha

doi:10.1158/0008-5472.can-05-0404

Public

Poor Survival Associated with the BRAF V600E Mutation in Microsatellite-Stable Colon Cancers

Published in Cancer Research • Jul 15, 2005

Authors:

Wade S. Samowitz

Carol Sweeney

Jennifer S. Herrick

Abstract

The BRAF V600E mutation has been associated with microsatellite instability and the CpG island methylator phenotype (CIMP) in colon cancer. We evaluated a large population-based sample of individuals with colon cancer to determine its relationship to survival and other clinicopathologic variables. T...

Subject

Microsatellite instability

Colorectal cancer

Hazard ratio

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