Microsatellite instability in non-neoplastic mucosa of patients with ulcerative colitis: effect of folate supplementation.

ML, Cravo; CM, Albuquerque; de Sousa L, Salazar; LM, Glória; P, Chaves; Pereira A, Dias; Leitão C, Nobre; MG, Quina; Mira F, Costa

doi:10.1111/j.1572-0241.1998.00592.x

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Microsatellite instability in non-neoplastic mucosa of patients with ulcerative colitis: effect of folate supplementation.

Shared by NobleBlocks on Nov 1, 1998 • 12:00 AM UTC

Authors:

Cravo ML

Albuquerque CM

Salazar de Sousa L

Abstract

Objective Microsatellite instability (MSI) detected in non-neoplastic mucosa of patients with ulcerative colitis has been ascribed to an excess of DNA damage associated with chronic inflammation. Folate deficiency, commonly found in patients with long-standing disease, could further contribute to th...

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