Endothelial dysfunction in diabetes

S. De Vriese, An; J. Verbeuren, Tony; Van de Voorde, Johan; Lameire, Norbert; M Vanhoutte, Paul

doi:10.1038/sj.bjp.0703393

Public

Endothelial dysfunction in diabetes

Published in British Journal of Pharmacology • Jul 1, 2000

Authors:

An S. De Vriese

Tony J. Verbeuren

Johan Van de Voorde

Abstract

Endothelial dysfunction plays a key role in the pathogenesis of diabetic vascular disease. The endothelium controls the tone of the underlying vascular smooth muscle through the production of vasodilator mediators. The endothelium-derived relaxing factors (EDRF) comprise nitric oxide (NO), prostacyc...

Subject

Endothelial dysfunction

Endothelium

Prostacyclin

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