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AKT/mTOR as Novel Targets of Polyphenol Piceatannol Possibly Contributing to Inhibition of Proliferation of Cultured Prostate Cancer Cells.

Published in ISRN urology • Jan 1, 2012
Authors:
Tze-Chen Hsieh
,
Chia-Yi Lin
,
Hung-Yun Lin

Abstract

The polyphenol piceatannol has shown inhibition against tyrosine and serine/threonine kinases. Whether piceatannol also exerts activity on the mammalian target of rapamycin (mTOR), a kinase involved in growth control of eukaryotic cells, is not known. In this study, we tested the effects of piceatan...

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