On the<i>in Vitro</i>and<i>in Vivo</i>Activity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

Y. Bowers, C.; A. Momany, Frank; A. Reynolds, G.; Hong, Anita

doi:10.1210/endo-114-5-1537

Public

On thein Vitroandin VivoActivity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

Published in Endocrinology • May 1, 1984

Authors:

C. Y. Bowers

Frank A. Momany

G. A. Reynolds

Abstract

His-DTrp-Ala-Trp-DPhe-LysNH2, [His1,Lys6] GHRP, is a new synthetic hexapeptide which specifically elicits a dosage-related release of GH in vitro and in vivo without a concomitant release of LH, FSH, TSH, or PRL and, in limited in vivo studies, insulin or glucagon. Our results indicate that this sma...

Subject

In vivo

Internal medicine

Endocrinology

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