On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone.

CY, Bowers; FA, Momany; GA, Reynolds; A, Hong

doi:10.1210/endo-114-5-1537

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On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone.

Shared by NobleBlocks on May 1, 1984 • 12:00 AM UTC

Authors:

Bowers CY

Momany FA

Reynolds GA

Abstract

His-DTrp-Ala-Trp-DPhe-LysNH2, [His1,Lys6] GHRP, is a new synthetic hexapeptide which specifically elicits a dosage-related release of GH in vitro and in vivo without a concomitant release of LH, FSH, TSH, or PRL and, in limited in vivo studies, insulin or glucagon. Our results indicate that this sma...

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