Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

M. Shaw, Leslie; Vanderstichele, Hugo; Knapik‐Czajka, Malgorzata; M. Clark, Christopher; S. Aisen, Paul; C. Petersen, Ronald; Blennow, Kaj; Soares, Holly; Simon, Adam; Lewczuk, Piotr; Dean, Robert; Siemers, Eric; Potter, William; M.‐Y. Lee, Virginia; Q. Trojanowski, John; Disease Neuroimaging Initiative, Alzheimer's

doi:10.1002/ana.21610

Public

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

Shared by NobleBlocks on Apr 1, 2009 • 12:00 AM UTC

Authors:

Leslie M. Shaw

Hugo Vanderstichele

Malgorzata Knapik‐Czajka

Abstract

Abstract Objective Develop a cerebrospinal fluid biomarker signature for mild Alzheimer's disease (AD) in Alzheimer's Disease Neuroimaging Initiative (ADNI) subjects. Methods Amyloid‐β 1 to 42 peptide (Aβ 1–42 ), total tau (t‐tau), and tau phosphorylated at the threonine 181 were measured in (1) cer...

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