Dapagliflozin Versus Glipizide as Add-on Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control With Metformin

A. Nauck, Michael; Del Prato, Stefano; J. Meier, Juris; Durán‐García, S.; Rohwedder, Katja; Elze, M.; Parikh, Shamik

doi:10.2337/dc11-0606

Public

Dapagliflozin Versus Glipizide as Add-on Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control With Metformin

Published in Diabetes Care • Aug 5, 2011

Authors:

Michael A. Nauck

Stefano Del Prato

Juris J. Meier

Abstract

OBJECTIVE: Although initially effective, sulfonylureas are associated with poor glycemic durability, weight gain, and hypoglycemia. Dapagliflozin, a selective inhibitor of sodium-glucose cotransporter 2 (SGLT2), reduces hyperglycemia by increasing urinary glucose excretion independent of insulin and...

Subject

Dapagliflozin

Glipizide

Medicine

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