Comparative evaluation of genotoxicity of captan in amphibian larvae (Xenopus laevis andPleurodeles waltl) using the comet assay and the micronucleus test

Mouchet, Florence; Gauthier, L.; Mailhes, Corinne; Ferrier, V.; Devaux, Alain

doi:10.1002/tox.20180

Public

Comparative evaluation of genotoxicity of captan in amphibian larvae (Xenopus laevis andPleurodeles waltl) using the comet assay and the micronucleus test

Published in Environmental Toxicology • Jan 1, 2006

Authors:

Florence Mouchet

L. Gauthier

Corinne Mailhes

Abstract

Captan (N-trichloromethylthio-4-cyclohexene-1,2-dicarboximide) is a fungicide used to inhibit the growth of many types of fungi on plants used as foodstuffs. The toxic and genotoxic potentials of captan were evaluated with the micronucleus test (MNT; AFNOR,2000) and the comet assay (CA) using amphib...

Subject

Pleurodeles

Captan

Genotoxicity

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