Toxicity and carcinogenicity of the <i>Fusanum monilzforine</i> metabolite, fumonisin B<sub>1</sub>, in rats

Gelderblom, W.C.A.; Kriek, N.P.J.; F. O. Marasas, W.; Thiel, P.G.

doi:10.1093/carcin/12.7.1247

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Toxicity and carcinogenicity of the Fusanum monilzforine metabolite, fumonisin B1, in rats

Published in Carcinogenesis • Jan 1, 1991

Authors:

W.C.A. Gelderblom

N.P.J. Kriek

W. F. O. Marasas

Abstract

A semi-purified corn-based diet containing 50 mg/kg of pure (not less than 90%) fumonisin B1 (FB1), isolated from culture material of Fusarium moniliforme strain MRC 826, was fed to a group of 25 rats over a period of 26 months. A control group of 25 rats received the same diet without FB1. Five rat...

Subject

Fumonisin B1

Hepatocellular carcinoma

Toxicity

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