Isolation and Characterization of Gal E Mutant Ty 21a of Salmonella typhi: A Candidate Strain for a Live, Oral Typhoid Vaccine

Germanier, R.; Fiirer, E.

doi:10.1093/infdis/131.5.553

Public

Isolation and Characterization of Gal E Mutant Ty 21a of Salmonella typhi: A Candidate Strain for a Live, Oral Typhoid Vaccine

Published in The Journal of Infectious Diseases • May 1, 1975

Authors:

R. Germanier

E. Fiirer

Abstract

A gal E mutant of Salmonella typhi was isolated; results obtained with Salmonella typhimurium and the mouse as a model for human typhoid fever indicated that this mutant has the potential for use as a live, oral typhoid vaccine. The mutant, Ty 21a, took up galactose from exogenous sources and accumu...

Subject

Typhoid fever

Immunogenicity

Microbiology

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