Type I and Type II mechanisms of antimicrobial photodynamic therapy: An in vitro study on gram‐negative and gram‐positive bacteria

Huang, Liyi; Yi, Xuan; Koide, Yuichiro; Zhiyentayev, Timur; Tanaka, Masamitsu; R. Hamblin, Michael

doi:10.1002/lsm.22045

Public

Type I and Type II mechanisms of antimicrobial photodynamic therapy: An in vitro study on gram‐negative and gram‐positive bacteria

Published in Lasers in Surgery and Medicine • Jul 3, 2012

Authors:

Liyi Huang

Xuan Yi

Yuichiro Koide

Abstract

BACKGROUND AND OBJECTIVES: Antimicrobial photodynamic therapy (APDT) employs a non-toxic photosensitizer (PS) and visible light, which in the presence of oxygen produce reactive oxygen species (ROS), such as singlet oxygen ((1) O(2), produced via Type II mechanism) and hydroxyl radical (HO(.), produ...

Subject

Chemistry

Bacteria

Gram-negative bacteria

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