Reactive oxygen species‐induced activation of ERK and p38 MAPK mediates PMA‐induced NETs release from human neutrophils

S. Keshari, Ravi; Verma, Anupam; Kumar Barthwal, Manoj; Dikshit, Madhu

doi:10.1002/jcb.24391

Public

Reactive oxygen species‐induced activation of ERK and p38 MAPK mediates PMA‐induced NETs release from human neutrophils

Published in Journal of Cellular Biochemistry • Sep 7, 2012

Authors:

Ravi S. Keshari

Anupam Verma

Manoj Kumar Barthwal

Abstract

Neutrophils/polymorphonuclear leukocytes (PMNs), an important component of innate immune system, release extracellular traps (NETs) to eliminate invaded pathogens; however understanding of the role of signaling molecules/proteins need to be elucidated. In the present study role of p38 MAPK and extra...

Subject

MAPK/ERK pathway

p38 mitogen-activated protein kinases

Cell biology

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