Salt-Inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer

Bon, Hélène; Wadhwa, Karan; Schreiner, A.; Osborne, Michelle; Carroll, Thomas; Ramos‐Montoya, Antonio; Ross‐Adams, Helen; Visser, Matthieu; Hoffmann, Ralf; A. Ahmed, Ahmed; E. Neal, David; G. Mills, Ian

doi:10.1158/1541-7786.mcr-13-0182-t

Public

Salt-Inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer

Published in Molecular Cancer Research • Dec 30, 2014

Authors:

Hélène Bon

Karan Wadhwa

A. Schreiner

Abstract

UNLABELLED: Salt-inducible kinase 2 (SIK2) is a multifunctional kinase of the AMPK family that plays a role in CREB1-mediated gene transcription and was recently reported to have therapeutic potential in ovarian cancer. The expression of this kinase was investigated in prostate cancer clinical speci...

Subject

CREB1

Biology

Gene knockdown

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