A Multi-Center Randomised Controlled Trial of Gatifloxacin versus Azithromycin for the Treatment of Uncomplicated Typhoid Fever in Children and Adults in Vietnam

Dolecek, Christiane; Thi Phi La, Tran; Ngọc Rạng, Nguyễn; Thi Phuong, Le; Vinh, Ha; Quoc Tuan, Phung; Cong Du, Doan; Thị Bảy, Nguyễn; Thanh Long, Duong; Bich Ha, Luong; Trung Binh, Nguyen; Thị Hồng, Nguyễn; Ngoc Dung, Pham; Ngoc Lanh, Mai; Van Be Bay, Phan; Anh Hó, Vô; Văn Minh Hoàng, Nguyễn; Thu Thi Nga, Tran; Thuy Chau, Tran; Schultsz, Constance; J. Dunstan, Sarah; Stepniewska, Kasia; Campbell, James; Song Diep, To; Basnyat, Buddha; Văn Vĩnh Châu, Nguyễn; Van Sach, Nguyen; Tran Chinh, Nguyen; Tinh Hien, Tran; Farrar, Jeremy

doi:10.1371/journal.pone.0002188

Public

A Multi-Center Randomised Controlled Trial of Gatifloxacin versus Azithromycin for the Treatment of Uncomplicated Typhoid Fever in Children and Adults in Vietnam

Published in PLoS ONE • May 21, 2008

Authors:

Christiane Dolecek

Tran Thi Phi La

Nguyễn Ngọc Rạng

Abstract

BACKGROUND: Drug resistant typhoid fever is a major clinical problem globally. Many of the first line antibiotics, including the older generation fluoroquinolones, ciprofloxacin and ofloxacin, are failing. OBJECTIVES: We performed a randomised controlled trial to compare the efficacy and safety of g...

Subject

Gatifloxacin

Medicine

Azithromycin

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