Validation of a dendron concept to tune colloidal stability, MRI relaxivity and bioelimination of functional nanoparticles

D. Walter, Adam; Garofalo, Antonio; Parat, Audrey; Jouhannaud, J.; Pourroy, G.; Voirin, Émilie; Laurent, Sophie; Bonazza, Pauline; Taleb, Jacqueline; Billotey, Claire; Vander Elst, Luce; N. Müller, Robert; Bégin‐Colin, Sylvie; Felder‐Flesch, Delphine

doi:10.1039/c4tb01954g

Public

Validation of a dendron concept to tune colloidal stability, MRI relaxivity and bioelimination of functional nanoparticles

Published in Journal of Materials Chemistry B • Jan 1, 2015

Authors:

Adam D. Walter

Antonio Garofalo

Audrey Parat

Abstract

The functionalization of spherical superparamagnetic iron oxide nanoparticles (SPION) of 10 nm with a linear monophosphonate (L1) and also PEGylated mono-phosphonated dendrons of growing generation (D2-G1, -G2 and -G3) yielded dendritic nano-objects of 15 to 30 nm in size, stable in physiological me...

Subject

Dendrimer

Colloid

Nanoparticle

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