Thermodynamic Parameters To Predict Stability of RNA/DNA Hybrid Duplexes

Sugimoto, Naoki; Nakano, Shu‐ichi; Katoh, Misa; Matsumura, Akiko; Nakamuta, Hiroyuki; Ohmichi, Tatsuo; Yoneyama, Mari; Sasaki, Muneo

doi:10.1021/bi00035a029

Public

Thermodynamic Parameters To Predict Stability of RNA/DNA Hybrid Duplexes

Published in Biochemistry • Sep 5, 1995

Authors:

Naoki Sugimoto

Shu‐ichi Nakano

Misa Katoh

Abstract

The thermodynamic parameters (delta H degree, delta S degree, and delta G degree 37) for 16 nearest-neighbor sets and one initiation factor are presented here in order to predict stability of RNA/DNA hybrid duplexes. To determine the nearest-neighbor parameters, thermodynamics for 68 different hybri...

Subject

RNA

Oligonucleotide

DNA

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