Regulation of Transcriptional Activity during the First and Second Cell Cycles in the Preimplantation Mouse Embryo

Transcription of endogenous genes in preimplantation 1- and 2-cell mouse embryos was determined by monitoring the incorporation of BrUTP by plasma membrane-permeabilized embryos. Incorporation is observed starting by mid-S phase in the 1-cell embryo and increases progressively; the amount of incorpo... View More