Critical role of interleukin-2 in the development of acute graft-versus-host disease.

CS, Via; FD, Finkelman

doi:10.1093/intimm/5.6.565

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Critical role of interleukin-2 in the development of acute graft-versus-host disease.

Shared by NobleBlocks on Jun 1, 1993 • 12:00 AM UTC

Authors:

Via CS

Finkelman FD

Abstract

Prior work using the parent-into-F1 model of graft-versus-host disease (GVHD) has shown that production of IL-2 by donor CD4+ T cells is an early, initiating event in either acute or stimulatory forms of GVHD. The aim of the present study was to determine whether acute GVHD could be prevented by blo...

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