Peginterferon Alfa-2a in Patients with Chronic Hepatitis C and Cirrhosis

Jenny Heathcote, E.; L. Shiffman, Mitchell; Graham E. Cooksley, W.; Dusheiko, Geoffrey; S. Lee, Samuel; A. Balart, Luis; Reindollar, Robert; Rajender Reddy, K.; L. Wright, Teresa; Lin, Amy; H. Hoffman, Joseph; De Pamphilis, Jean

doi:10.1056/nejm200012073432302

Public

Peginterferon Alfa-2a in Patients with Chronic Hepatitis C and Cirrhosis

Published in New England Journal of Medicine • Dec 7, 2000

Authors:

E. Jenny Heathcote

Mitchell L. Shiffman

W. Graham E. Cooksley

Abstract

BACKGROUND: Chronic hepatitis C virus (HCV) infection in patients with cirrhosis is difficult to treat. In patients with chronic hepatitis C but without cirrhosis, once-weekly administration of interferon modified by the attachment of a 40-kd branched-chain polyethylene glycol moiety (peginterferon ...

Subject

Medicine

Cirrhosis

Gastroenterology

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