Synthesis of Mosaic Peptidoglycan Cross-bridges by Hybrid Peptidoglycan Assembly Pathways in Gram-positive Bacteria

Arbeloa, Ana; Hugonnet, Jean‐Emmanuel; Sentilhes, Anne‐Charlotte; Josseaume, Nathalie; Dubost, Lionnel; Monsempès, Christelle; Blanot, Didier; Brouard, Jean‐Paul; Arthur, Michel

doi:10.1074/jbc.m407149200

Public

Synthesis of Mosaic Peptidoglycan Cross-bridges by Hybrid Peptidoglycan Assembly Pathways in Gram-positive Bacteria

Published in Journal of Biological Chemistry • Jul 27, 2004

Authors:

Ana Arbeloa

Jean‐Emmanuel Hugonnet

Anne‐Charlotte Sentilhes

Abstract

The peptidoglycan cross-bridges of Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium consist of the sequences Gly(5), l-Ala(2), and d-Asx, respectively. Expression of the fmhB, femA, and femB genes of S. aureus in E. faecalis led to the production of peptidoglycan precursors sub...

Subject

Peptidoglycan

Enterococcus faecalis

Penicillin binding proteins

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