Impact of genotype-guided dosing on anticoagulation visits for adults starting warfarin: a randomized controlled trial.

DE, Jonas; JP, Evans; HL, McLeod; S, Brode; LA, Lange; ML, Young; BB, Shilliday; MM, Bardsley; NJ, Swinton-Jenkins; KE, Weck

doi:10.2217/pgs.13.145

Public

Impact of genotype-guided dosing on anticoagulation visits for adults starting warfarin: a randomized controlled trial.

Shared by NobleBlocks on Oct 1, 2013 • 12:00 AM UTC

Authors:

Jonas DE

Evans JP

McLeod HL

Abstract

Aim This study aimed to assess the effectiveness of genotype-guided warfarin dosing.Patients & methods A total of 109 adults were randomized to receive initial dosing as determined by an algorithm containing genetic (VKORC1 and CYP2C9) plus clinical information or only clinical information. Primary ...

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