ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development

Hee Choi, Young; Yu, Ai‐Ming

doi:10.2174/138161282005140214165212

Public

ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development

Published in Current Pharmaceutical Design • Feb 1, 2014

Authors:

Young Hee Choi

Ai‐Ming Yu

Abstract

Multidrug resistance (MDR) is a serious problem that hampers the success of cancer pharmacotherapy. A common mechanism is the overexpression of ATP-binding cassette (ABC) efflux transporters in cancer cells such as P-glycoprotein (P-gp/ABCB1), multidrug resistance-associated protein 1 (MRP1/ABCC1) a...

Subject

Abcg2

ATP-binding cassette transporter

Efflux

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!