Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulin-dependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group.

Marre, Michel; Jeunemaı̂tre, Xavier; Gallois, Yves; Rodier, M.; Châtellier, Gilles; Sert, Caroline; Dusselier, L.; Kahal, Z; Chaillous, Lucy; Halimi, S.; Müller, Ulrich; Sackmann, H.; Bauduceau, B.; Bled, F.; Passa, P; Alhenc‐Gelas, F

doi:10.1172/jci119321

Public

Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulin-dependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group.

Published in Journal of Clinical Investigation • Apr 1, 1997

Authors:

Michel Marre

Xavier Jeunemaı̂tre

Yves Gallois

Abstract

Diabetic nephropathy is a glomerular disease due to uncontrolled diabetes and genetic factors. It can be caused by glomerular hypertension produced by capillary vasodilation, due to diabetes, against constitutional glomerular resistance. As angiotensin II increases glomerular pressure, we studied th...

Subject

Internal medicine

Medicine

Endocrinology

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