Cyvadic in advanced soft tissue sarcoma: a randomized study comparing two schedules. A study of the EORTC Soft Tissue and Bone Sarcoma Group.

HM, Pinedo; VH, Bramwell; HT, Mouridsen; R, Somers; CP, Vendrik; A, Santoro; J, Buesa; T, Wagener; Oosterom AT, van; Unnik JA, van

doi:10.1002/1097-0142(19840501)53:9<1825::aid-cncr2820530904>3.0.co;2-z

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Cyvadic in advanced soft tissue sarcoma: a randomized study comparing two schedules. A study of the EORTC Soft Tissue and Bone Sarcoma Group.

Shared by NobleBlocks on May 1, 1984 • 12:00 AM UTC

Authors:

Pinedo HM

Bramwell VH

Mouridsen HT

Abstract

Two hundred forty-six adults with advanced progressive soft tissue sarcoma received combination chemotherapy with cyclophosphamide, vincristine, Adriamycin (doxorubicin), and DTIC. They were randomly allocated to receive the four drugs simultaneously every 4 weeks (S1: CYVADIC), or pairs of drugs (S...

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