The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology

Pezawas, Lukas; A. Verchinski, Beth; S. Mattay, Venkata; H. Callicott, Joseph; Kolachana, Bhaskar; E. Straub, Richard; Egan, Michael; Meyer‐Lindenberg, Andreas; R. Weinberger, Daniel

doi:10.1523/jneurosci.2680-04.2004

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The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology

Published in Journal of Neuroscience • Nov 10, 2004

Authors:

Lukas Pezawas

Beth A. Verchinski

Venkata S. Mattay

Abstract

A variation in the BDNF gene (val66met) affects the function of BDNF in neurons, predicts variation in human memory, and is associated with several neurological and psychiatric disorders. Here, we show that, in magnetic resonance imaging scans of a large sample of normal individuals, this polymorphi...

Subject

Brain morphometry

Neuroscience

Neurotrophic factors

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