Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

Arthur Campfield, L.; J. Smith, Françoise; Guisez, Yves; Devos, René; Burn, Paul

doi:10.1126/science.7624778

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Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

Published in Science • Jul 28, 1995

Authors:

L. Arthur Campfield

Françoise J. Smith

Yves Guisez

Abstract

The recent positional cloning of the mouse ob gene and its human homology has provided the basis to investigate the potential role of the ob gene product in body weight regulation. A biologically active form of recombinant mouse OB protein was overexpressed and purified to near homogeneity from a ba...

Subject

Recombinant DNA

Peripheral

SIGNAL (programming language)

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