Autophagy is a protective mechanism in normal cartilage, and its aging‐related loss is linked with cell death and osteoarthritis

Caramés, B.; Taniguchi, Noboru; Otsuki, Shuhei; J. Blanco, Francisco; Lotz, Martin

doi:10.1002/art.27305

Public

Autophagy is a protective mechanism in normal cartilage, and its aging‐related loss is linked with cell death and osteoarthritis

Published in Arthritis & Rheumatism • Feb 25, 2010

Authors:

B. Caramés

Noboru Taniguchi

Shuhei Otsuki

Abstract

OBJECTIVE: Autophagy is a process for turnover of intracellular organelles and molecules that protects cells during stress responses. We undertook this study to evaluate the potential roles of Unc-51-like kinase 1 (ULK1), an inducer of autophagy, Beclin1, a regulator of autophagy, and microtubule-as...

Subject

Autophagy

ULK1

Cell biology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!