Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

D’Amours, Damien; Desnoyers, Serge; D’Silva, Icy; G. Poirier, Guy

doi:10.1042/bj3420249

Public

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Published in Biochemical Journal • Aug 24, 1999

Authors:

Damien D’Amours

Serge Desnoyers

Icy D’Silva

Abstract

Poly(ADP-ribosyl)ation is a post-translational modification of proteins. During this process, molecules of ADP-ribose are added successively on to acceptor proteins to form branched polymers. This modification is transient but very extensive in vivo, as polymer chains can reach more than 200 units o...

Subject

Poly ADP ribose polymerase

Ribose

Polymerase

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