Enhand secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina ropria monouclear cells from patients with ulcretive cilitis and Crohn's disease

REINECKER, H-C; Steffen, Martín; Witthoeft, T.; PFLUEGER, I; Schreiber, Stefan; P. MacDermott, Richard; Raedler, Andreas

doi:10.1111/j.1365-2249.1993.tb05997.x

Public

Enhand secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina ropria monouclear cells from patients with ulcretive cilitis and Crohn's disease

Published in Clinical & Experimental Immunology • Oct 1, 1993

Authors:

H-C REINECKER

Martín Steffen

T. Witthoeft

Abstract

The perpetuation of inflammation in ulcerative colitis and Crohn's disease may be regulated in part by an increased secretion of proinflammatory cytokines due to either an appropriate response to initial stimulating agents, and/or due to an impaired down-regulation of cytokine secretion. The aim of ...

Subject

Proinflammatory cytokine

Ulcerative colitis

Lamina propria

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