Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty

I. Eriksson, Bengt; C. Borris, Lars; J. Friedman, Richard; Haas, Sylvia; V. Huisman, Menno; K. Kakkar, Ajay; J. Bandel, Tiemo; Beckmann, Horst; Muehlhofer, Eva; Misselwitz, Frank; Geerts, William

doi:10.1056/nejmoa0800374

Public

Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty

Published in New England Journal of Medicine • Jun 25, 2008

Authors:

Bengt I. Eriksson

Lars C. Borris

Richard J. Friedman

Abstract

BACKGROUND: This phase 3 trial compared the efficacy and safety of rivaroxaban, an oral direct inhibitor of factor Xa, with those of enoxaparin for extended thromboprophylaxis in patients undergoing total hip arthroplasty. METHODS: In this randomized, double-blind study, we assigned 4541 patients to...

Subject

Medicine

Rivaroxaban

Pulmonary embolism

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