Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

Zhang, Yi; Ng, Huck‐Hui; Erdjument-Bromage, H.; Tempst, Paul; Bird, Adrian; Reinberg, Danny

doi:10.1101/gad.13.15.1924

Public

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

Published in Genes & Development • Aug 1, 1999

Authors:

Yi Zhang

Huck‐Hui Ng

H. Erdjument-Bromage

Abstract

ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation represent mechanisms to alter nucleosome structure. NuRD is a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. The histone deacetylases HDAC1 and HDAC2 and the histone binding ...

Subject

Biology

DNA

DNA methylation

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