Requirement of <i>bic/microRNA-155</i> for Normal Immune Function

Rodriguez, Antony; Vigorito, Elena; Clare, Simon; Warren, Madhuri; Couttet, Philippe; R. Soond, Dalya; van Dongen, Stijn; Grocock, Russell; Pratim Das, Partha; A. Miska, Eric; Vetrie, David; Okkenhaug, Klaus; J. Enright, Anton; Dougan, Gordon; Turner, Martin; Bradley, Allan

doi:10.1126/science.1139253

Public

Requirement of bic/microRNA-155 for Normal Immune Function

Published in Science • Apr 26, 2007

Authors:

Antony Rodriguez

Elena Vigorito

Simon Clare

Abstract

MicroRNAs are a class of small RNAs that are increasingly being recognized as important regulators of gene expression. Although hundreds of microRNAs are present in the mammalian genome, genetic studies addressing their physiological roles are at an early stage. We have shown that mice deficient for...

Subject

microRNA

Biology

Immune system

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