MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells.

D, Li; P, Yang; Q, Xiong; X, Song; X, Yang; L, Liu; W, Yuan; YC, Rui

doi:10.1097/hjh.0b013e32833a4922

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MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells.

Shared by NobleBlocks on Aug 1, 2010 • 12:00 AM UTC

Authors:

Li D

Yang P

Xiong Q

Abstract

Background Endothelin-1 (ET-1) is considered to be one of the most potent and long-lasting vasoconstrictive peptides, but the mechanisms on the regulation of ET-1 expression are not fully understood.Method and results In this study, we found that microRNA (miR)-125a-5p and miR-125b-5p are highly exp...

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