Trajectories of Agouti-Related Protein and Leptin Levels During Antipsychotic-Associated Weight Gain in Patients With Schizophrenia

Ehrlich, Stefan; Leopold, Karolina; V. Merle, Julia; Theophil, Ines; Haag, Wiebke; Lautenschlager, Marion; Schaefer, Martin

doi:10.1097/jcp.0b013e318270e5c5

Public

Trajectories of Agouti-Related Protein and Leptin Levels During Antipsychotic-Associated Weight Gain in Patients With Schizophrenia

Published in Journal of Clinical Psychopharmacology • Nov 6, 2012

Authors:

Stefan Ehrlich

Karolina Leopold

Julia V. Merle

Abstract

OBJECTIVE: Some but not all second-generation antipsychotics can induce considerable weight gain and metabolic syndrome. Although the exact biochemical mechanisms for these adverse effects are unclear, appetite-regulating neuropeptides of the central nervous system are thought to be implicated in th...

Subject

Ziprasidone

Olanzapine

Leptin

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