Chromosomal alterations in exfoliated urothelial cells from bladder cancer cases and healthy men: a prospective screening study

Bonberg, Nadine; Pesch, Beate; Behrens, Thomas; Johnen, Georg; Taeger, Dirk; Gawrych, Katarzyna; Schwentner, Christian; Wellhäußer, Harald; Kluckert, Matthias; Leng, G.; Nasterlack, Michael; Oberlinner, Christoph; Stenzl, Arnulf; Brüning, Thomas

doi:10.1186/1471-2407-14-854

Public

Chromosomal alterations in exfoliated urothelial cells from bladder cancer cases and healthy men: a prospective screening study

Published in BMC Cancer • Nov 20, 2014

Authors:

Nadine Bonberg

Beate Pesch

Thomas Behrens

Abstract

BACKGROUND: Chromosomal instability in exfoliated urothelial cells has been associated with the development of bladder cancer. Here, we analyzed the accumulation of copy number variations (CNVs) using fluorescence in situ hybridization in cancer cases and explored factors associated with the detecti...

Subject

Polysomy

Bladder cancer

Copy-number variation

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