Activated STING in a Vascular and Pulmonary Syndrome

Liu, Yu; A. de Jesus, Adriana; Marrero, Bernadette; Yang, Dan; Ramsey, Suzanne; A. Montealegre Sanchez, Gina; Tenbrock, Klaus; Wittkowski, Helmut; Y. Jones, Olcay; Kuehn, Hyesun; Richard Lee, Chyi‐Chia; A. DiMattia, Michael; W. Cowen, Edward; González, B; Palmer, Ira; J. DiGiovanna, John; Biancotto, Angélique; Kim, Hanna; Lin Tsai, Wen; M. Trier, Anna; Huang, Yan; L. Stone, Deborah; Hill, Suvimol; Kim, HyeSoon; St. Hilaire, Cynthia; Gurprasad, Shakuntala; Plass, N; Chapelle, Dawn; Horkayne‐Szakaly, Iren; Foell, Dirk; Barysenka, Andrei; Candotti, Fabio; M. Holland, Steven; D. Hughes, Jason; Mehmet, Huseyin; C. Issekutz, Andrew; Raffeld, M; McElwee, Joshua; Fontana, JÉRǑMe; P. Minniti, Caterina; Moir, Susan; L. Kastner, Daniel; Gadina, Massimo; Steven, A.C.; T. Wingfield, Paul; R. Brooks, Stephen; D. Rosenzweig, Sergio; A. Fleisher, Thomas; Deng, Zuoming; Boehm, Manfred; S. Paller, Amy; Goldbach‐Mansky, Raphaela

doi:10.1056/nejmoa1312625

Public

Activated STING in a Vascular and Pulmonary Syndrome

Published in New England Journal of Medicine • Jul 16, 2014

Authors:

Yu Liu

Adriana A. de Jesus

Bernadette Marrero

Abstract

BACKGROUND: The study of autoinflammatory diseases has uncovered mechanisms underlying cytokine dysregulation and inflammation. METHODS: We analyzed the DNA of an index patient with early-onset systemic inflammation, cutaneous vasculopathy, and pulmonary inflammation. We sequenced a candidate gene, ...

Subject

Medicine

Sting

Cardiology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!