Cytoprotective effects of 12-oxo phytodienoic acid, a plant-derived oxylipin jasmonate, on oxidative stress-induced toxicity in human neuroblastoma SH-SY5Y cells

Taki-Nakano, Nozomi; Ohzeki, Hiromitsu; Kotera, Jun; Ohta, Hiroyuki

doi:10.1016/j.bbagen.2014.09.003

Public

Cytoprotective effects of 12-oxo phytodienoic acid, a plant-derived oxylipin jasmonate, on oxidative stress-induced toxicity in human neuroblastoma SH-SY5Y cells

Published in Biochimica et Biophysica Acta (BBA) - General Subjects • Sep 16, 2014

Authors:

Nozomi Taki-Nakano

Hiromitsu Ohzeki

Jun Kotera

Abstract

BACKGROUND: Jasmonates are plant lipid-derived oxylipins that act as key signaling compounds when plants are under oxidative stress, but little is known about their functions in mammalian cells. Here we investigated whether jasmonates could protect human neuroblastoma SH-SY5Y cells against oxidative...

Subject

Oxidative stress

Reactive oxygen species

Glutathione

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