Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development

Leah Etheridge, S.; Ray, Saugata; Li, Shuangding; S. Hamblet, Natasha; Lijam, Nardos; Tsang, Michael; M. Greer, Joy; Kardos, Natalie; Wang, Jianbo; J. Sussman, Daniel; Chen, Ping; Wynshaw‐Boris, Anthony

doi:10.1371/journal.pgen.1000259

Public

Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development

Published in PLoS Genetics • Nov 13, 2008

Authors:

S. Leah Etheridge

Saugata Ray

Shuangding Li

Abstract

Dishevelled (Dvl) proteins are important signaling components of both the canonical beta-catenin/Wnt pathway, which controls cell proliferation and patterning, and the planar cell polarity (PCP) pathway, which coordinates cell polarity within a sheet of cells and also directs convergent extension ce...

Subject

Dishevelled

Convergent extension

Biology

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