CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.

CV, Edi; L, Djogbénou; AM, Jenkins; K, Regna; MA, Muskavitch; R, Poupardin; CM, Jones; J, Essandoh; GK, Kétoh; MJ, Paine; BG, Koudou; MJ, Donnelly; H, Ranson; D, Weetman

doi:10.1371/journal.pgen.1004236

Public

CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.

Shared by NobleBlocks on Mar 20, 2014 • 12:00 AM UTC

Authors:

Edi CV

Djogbénou L

Jenkins AM

Abstract

Malaria control relies heavily on pyrethroid insecticides, to which susceptibility is declining in Anopheles mosquitoes. To combat pyrethroid resistance, application of alternative insecticides is advocated for indoor residual spraying (IRS), and carbamates are increasingly important. Emergence of a...

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