An atlas of active enhancers across human cell types and tissues

Andersson, Robin; Gebhard, Claudia; Miguel-Escalada, Irene; Hoof, Ilka; Bornholdt, Jette; Boyd, Mette; Chen, Yun; Zhao, Xiaobei; Schmidl, Christian; Suzuki, Takahiro; Ntini, Evgenia; Arner, Erik; Valen, Eivind; Li, Kang; Schwarzfischer, Lucia; Glatz, Dagmar; Raithel, Johanna; Lilje, Berit; Rapin, Nicolas; Otzen Bagger, Frederik; Jørgensen, Mette; Refsing Andersen, Peter; Bertin, Nicolas; J. L. Rackham, Owen; Maxwell Burroughs, A.; Kenneth Baillie, J.; Ishizu, Yuri; Shimizu, Yuri; Furuhata, Erina; Maeda, Shiori; Negishi, Yutaka; Mungall, Chris; F. Meehan, Terrence; Lassmann, Timo; Itoh, Masayoshi; Kawaji, Hideya; Kondo, Naoto; Kawai, Jun; Lennartsson, Andreas; O. Daub, Carsten; Heutink, Peter; Hume, David; Heick Jensen, Torben; Suzuki, Harukazu; Hayashizaki, Yoshihide; Müller, Ferenc; R. R. Forrest, Alistair; Carninci, Piero; Rehli, Michael; Sandelin, Albin

doi:10.1038/nature12787

Public

An atlas of active enhancers across human cell types and tissues

Published in Nature • Mar 1, 2014

Authors:

Robin Andersson

Claudia Gebhard

Irene Miguel-Escalada

Abstract

Enhancers control the correct temporal and cell-type-specific activation of gene expression in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial to understand the regulation of differentiation and homeostasis. Here we use the FANTOM5 panel of samples, cov...

Subject

Atlas (anatomy)

Enhancer

Computational biology

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