Protective and Enhancing HLA Alleles, HLA-DRB1*0901 and HLA-A*24, for Severe Forms of Dengue Virus Infection, Dengue Hemorrhagic Fever and Dengue Shock Syndrome

Thị Phương Lan, Nguyễn; Kikuchi, Mihoko; Thi Que Huong, Vu; Quang Ha, Do; Thi Thúy, Trần; Dinh Tham, Vo; Mạnh Tuấn, Hà; Van Tuong, Vo; Thi Phi Nga, Cao; Van Dat, Tran; Oyama, Toshifumi; Morita, Kouichi; Yasunami, Michio; Hirayama, Kenji

doi:10.1371/journal.pntd.0000304

Public

Protective and Enhancing HLA Alleles, HLA-DRB10901 and HLA-A24, for Severe Forms of Dengue Virus Infection, Dengue Hemorrhagic Fever and Dengue Shock Syndrome

Published in PLoS neglected tropical diseases • Sep 30, 2008

Authors:

Nguyễn Thị Phương Lan

Mihoko Kikuchi

Vu Thi Que Huong

Abstract

BACKGROUND: Dengue virus (DV) infection is one of the most important mosquito-borne diseases in the tropics. Recently, the severe forms, dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), have become the leading cause of death among children in Southern Vietnam. Protective and/or pathog...

Subject

Dengue fever

Dengue virus

Immunology

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