Dabigatran versus Warfarin in Patients with Mechanical Heart Valves

W. Eikelboom, John; J. Connolly, Stuart; Brueckmann, Martina; B. Granger, Christopher; Pieter Kappetein, A.; J. Mack, Michael; Blatchford, Jon; Devenny, Kevin; Friedman, Jeffrey; Guiver, Kelly; Harper, Ruth; Khder, Yasser; T. Lobmeyer, Maximilian; Maas, Hugo; Voigt, Jens‐Uwe; L. Simoons, Maarten; Van de Werf, Frans

doi:10.1056/nejmoa1300615

Public

Dabigatran versus Warfarin in Patients with Mechanical Heart Valves

Published in New England Journal of Medicine • Sep 1, 2013

Authors:

John W. Eikelboom

Stuart J. Connolly

Martina Brueckmann

Abstract

BACKGROUND: Dabigatran is an oral direct thrombin inhibitor that has been shown to be an effective alternative to warfarin in patients with atrial fibrillation. We evaluated the use of dabigatran in patients with mechanical heart valves. METHODS: In this phase 2 dose-validation study, we studied two...

Subject

Dabigatran

Medicine

Warfarin

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!