Treatment of early seropositive rheumatoid arthritis: Doxycycline plus methotrexate versus methotrexate alone

R. O’Dell, James; Elliott, J; A. Mallek, Jack; R. Mikuls, Ted; A Weaver, Cynthia; L. Glickstein, Scott; M. Blakely, Kent; Hausch, Raymond; Leff, R.

doi:10.1002/art.21620

Public

Treatment of early seropositive rheumatoid arthritis: Doxycycline plus methotrexate versus methotrexate alone

Published in Arthritis & Rheumatism • Jan 30, 2006

Authors:

James R. O’Dell

J Elliott

Jack A. Mallek

Abstract

OBJECTIVE: To compare the efficacy of doxycycline plus methotrexate (MTX) versus MTX alone in the treatment of early seropositive rheumatoid arthritis (RA), and to attempt to differentiate the antibacterial and antimetalloproteinase effects of doxycycline. METHODS: Sixty-six patients with seropositi...

Subject

Doxycycline

Rheumatoid arthritis

Methotrexate

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