Psychopharmacological profile of a new chroman derivative with 5‐hydroxytryptamine1A agonist properties: S 20499 (+)

Abstract S 20499 is the (+) enantiomer of the racemic compound S 20244 (4‐N‐(methoxychromane‐3‐yl) N‐propylamino butyl‐8‐azaspiro 4,5 decane‐7,9 dione), a novel 5‐hydroxytryptamine 1A (5‐HT 1A ) agonist. The present experiments examined the potential anxiolytic and 5‐HT 1A agonist activity of S 2049... View More