Quinolinic acid in cerebrospinal fluid and serum in HIV‐1 Infection: Relationship to clinical and neurological status

P. Heyes, Melvyn; J. Brew, Bruce; Martin, Alex; W. Price, Richard; Μ. Salazar, Andres; J. Sidtis, John; A. Yergey, James; Maral Mouradian, M.; E. Sadler, Abigail; G. Keilp, John; R. Rubinow, David; P. Markey, Sanford

doi:10.1002/ana.410290215

Public

Quinolinic acid in cerebrospinal fluid and serum in HIV‐1 Infection: Relationship to clinical and neurological status

Published in Annals of Neurology • Feb 1, 1991

Authors:

Melvyn P. Heyes

Bruce J. Brew

Alex Martin

Abstract

Quinolinic acid is an "excitotoxic" metabolite and an agonist of N-methyl-D-aspartate receptors. Of patients infected with human immunodeficiency virus type 1 (HIV-1) who were neurologically normal or exhibited only equivocal and subclinical signs of the acquired immunodeficiency syndrome (AIDS) dem...

Subject

Quinolinic acid

Cerebrospinal fluid

Dementia

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