The alpha1-Adrenergic Antagonist Prazosin Ameliorates Combat Trauma Nightmares in Veterans With Posttraumatic Stress Disorder

A. Raskind, Murray; J. Dobie, Dorcas; D. Kanter, Evan; C. Petrie, Eric; E. Thompson, Charles; R. Peskind, Elaine

doi:10.4088/jcp.v61n0208

Public

The alpha1-Adrenergic Antagonist Prazosin Ameliorates Combat Trauma Nightmares in Veterans With Posttraumatic Stress Disorder

Published in The Journal of Clinical Psychiatry • Feb 15, 2000

Authors:

Murray A. Raskind

Dorcas J. Dobie

Evan D. Kanter

Abstract

BACKGROUND: Central nervous system (CNS) adrenergic hyperresponsiveness may be involved in the pathophysiology of posttraumatic stress disorder (PTSD). Two Vietnam combat veterans with PTSD prescribed the centrally active alpha1-adrenergic antagonist prazosin for symptoms of benign prostatic hypertr...

Subject

Prazosin

Nightmare

Psychology

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