Upregulation of Neurotoxic Serine Proteases, Prothrombin, and Protease-Activated Receptor 1 Early After Spinal Cord Injury

A. Citron, Bruce; V. Smirnova, Irina; M. Arnold, Paul; W. Festoff, Barry

doi:10.1089/neu.2000.17.1191

Public

Upregulation of Neurotoxic Serine Proteases, Prothrombin, and Protease-Activated Receptor 1 Early After Spinal Cord Injury

Published in Journal of Neurotrauma • Dec 1, 2000

Authors:

Bruce A. Citron

Irina V. Smirnova

Paul M. Arnold

Abstract

Apoptosis, well-established in development and now also in degenerative disease, occurs with regularity in several cell compartments early after controlled contusion spinal cord injury (SCI). Cell death in astrocytic, microglial, and neuronal populations peaks at 3 days, while oligodendroglial apopt...

Subject

Proteases

Serine protease

Caspase

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!