Characterization of Insulin and Insulin-Like Growth Factor I Receptors of Purified Leydig Cells and Their Role in Steroidogenesis in Primary Culture: A Comparative Study*

Lin, T.; F. Haskell, Joyce; Vinson, Nancy; Terracio, Louis

doi:10.1210/endo-119-4-1641

Public

Characterization of Insulin and Insulin-Like Growth Factor I Receptors of Purified Leydig Cells and Their Role in Steroidogenesis in Primary Culture: A Comparative Study*

Published in Endocrinology • Oct 1, 1986

Authors:

T. Lin

Joyce F. Haskell

Nancy Vinson

Abstract

Characterization of insulin and type I insulin-like growth factor (IGF-I) receptors and the effects of insulin and IGF-I on steroidogenesis were evaluated by using purified adult Leydig cells from Sprague-Dawley rats. Purified Leydig cells were found to contain both high and low affinity binding sit...

Subject

Internal medicine

Endocrinology

Insulin

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