Basal Calcium Entry in Retinal Pigment Epithelial Cells Is Mediated by TRPC Channels

̈nke Wimmers, So; Strauß, Olaf

doi:10.1167/iovs.07-0412

Public

Basal Calcium Entry in Retinal Pigment Epithelial Cells Is Mediated by TRPC Channels

Published in Investigative Ophthalmology & Visual Science • Nov 30, 2007

Authors:

So ̈nke Wimmers

Olaf Strauß

Abstract

PURPOSE: Ca(2+) is a major regulator of cell function. In the retinal pigment epithelium (RPE), intracellular free Ca(2+) concentration ([Ca(2+)](i)) is essential for the maintenance of normal retinal function. Therefore, accurate control of [Ca(2+)](i) is vital in these cells. Because Ca(2+) is per...

Subject

TRPC

Cell biology

Retinal pigment epithelium

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