Nephrectomy Followed by Interferon Alfa-2b Compared with Interferon Alfa-2b Alone for Metastatic Renal-Cell Cancer

C. Flanigan, Robert; E. Salmon, Sydney; A. Blumenstein, Brent; I. Bearman, Scott; Roy, Vivek; C. McGrath, Patrick; R. Caton, J.; C. Munshi, Nikhil; David Crawford, E.

doi:10.1056/nejmoa003013

Public

Nephrectomy Followed by Interferon Alfa-2b Compared with Interferon Alfa-2b Alone for Metastatic Renal-Cell Cancer

Published in New England Journal of Medicine • Dec 6, 2001

Authors:

Robert C. Flanigan

Sydney E. Salmon

Brent A. Blumenstein

Abstract

BACKGROUND: The value of nephrectomy in metastatic renal-cell cancer has long been debated. Several nonrandomized studies suggest a higher rate of response to systemic therapy and longer survival in patients who have undergone nephrectomy. METHODS: We randomly assigned patients with metastatic renal...

Subject

Medicine

Nephrectomy

Renal cell carcinoma

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